Indigenous 3D Bio-printer to Print Human Tissues
Article by : India Science Wire
Indian Tech Startup Avay Biosciences’ 3D Bio-Printer “Mito Plus”, a native state-of-the art bio-printer, has proven to be useful in the printing of human tissues.
BThe process of tissue replication using io printing supports living cells and provides them with the opportunity to be nurtured. This is a possible alternative to organ transplantation. The technique can be used to produce functional human tissues, such as skin, using biomaterials and bio-inks specifically engineered to print artificial living tissue.
An indigenous state-of-the-art 3D Bio-Printer ‘Mito Plus’ launched by Indian Tech Startup Avay Biosciences has been found to be helpful in printing human tissues. The Bengaluru Tech Summit, November 16-18 2022 saw the launch of Mito Plus. Mito Plus, the prototype of the product was inaugurated at Bangalore’s Indian Institute of Science. This is the most highly ranked institute in science research according to NIRF Rankings.
Mito Plus 3D Bio-Printer is an upgraded version. This was created with inputs from the prototype developed at IISc by Dr. Bikramjit Bazu. The prototype was also used as a basis for the development of the Mito Plus. This is India’s most advanced 3D printer. Avay Biosciences is a fully indigenous software and hardware developer for Bio 3D printing solutions.
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“MITO plus is an advanced bio-printer at its price range which can be used to print a wide range of biomaterials. The printer has an integrated UV curing feature, HEPA filter, and temperature control options. This allows the printer’s print head and bed to be warmed up to 80 degrees Celsius and cooled down to four degrees celsius respectively. MITO plus can be used for pharmaceutical drug discovery and drug testing applications, it can also be used in cancer biology and cosmetology applications,” said Manish Amin, Chief Executive Officer, Avay Biosciences.
While bio-printers can be used in the same way that other 3D printers, there is one key difference. Instead of using metal, plastic or powders to deliver materials, bio-printers use biomaterials that can include live cells to create complex structures such as skin, liver, and other tissue. Through science and technology, 3D Bio-printing provides a gift that is unique to mankind. Many challenges remain to be overcome.
“There is still a long way to go before we can create fully functioning and viable organs for human transplant,” Amin explained.
“We are working on having our printers develop skin – the most common type of layered tissue that could help victims of severe burns. These tissues can also be used for toxicology screens and other testing mechanisms,” said Suhridh Sundaram, Chief Operating Officer, Avay Biosciences.
Bio-printing typically uses polymers that attempt to replicate the extracellular matrix (ECM), native to a specific cell. Because future research is dependent on the availability of affordable bio-printers, it’s crucial to have cost-effective options. Bioprinting is possible if animal cells are used. It can also be used to produce artificial meat.
Apart from premier Research and Development institutions such as IIT Madras and IISc Bangalore, the tech startup’s customers and collaborators include the Institute of Chemical Technology (ICT), Mumbai; National Institute of Pharmaceutical Education And Research (NIPER), Hyderabad; and BITS Pilani (Goa Campus).